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A new study from China showed that antibodies faded quickly in both asymptomatic and symptomatic COVID-19 patients during convalescence, raising questions about whether the illness leads to any lasting immunity to the virus afterward.

The study, which focused on 37 asymptomatic and 37 symptomatic patients, showed that more than 90% of both groups showed steep declines in levels of SARS-COV-2–specific immunoglobulin G (IgG) antibodies within 2 to 3 months after onset of infection, according to a report published yesterday in Nature Medicine. Further, 40% of the asymptomatic group tested negative for IgG antibodies 8 weeks after they were released from isolation.

The authors said the findings suggest that it could be risky to assume that recovered patients are immune to reinfection, which may have implications for how long to maintain physical distancing restrictions.

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In combination with certain previous findings on COVID-19 antibodies, the researchers concluded that their results "might indicate the risks of using COVID-19 'immunity passports' and support the prolongation of public health interventions, including social distancing, hygiene, isolation of high-risk groups and widespread testing."

The study did not address cellular immunity to COVID-19—that is, immune responses involving T-cells rather than antibodies. Some previous studies have found SARS-CoV–specific T-cells in high percentages of convalescent COVID-19 patients.

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Originally posted by jon-nyc:
I’m happy to get vaccinated once a month.