Will you get the vaccine?

23 November 2020, 08:01 PM

It's kind of interesting to compare the descriptions of the clinical trials conducted by Pfizer, Moderna, and AstraZeneca.

BioNTech/Pfizer:
https://clinicaltrials.gov/ct2/show/NCT04368728

Moderna: https://clinicaltrials.gov/ct2...na&&draw&=2&&rank&=5

AstraZeneca: https://clinicaltrials.gov/ct2/show/NCT04516746

Add Johnson&Johnson Janssen, which is a single dose vaccine:

https://clinicaltrials.gov/ct2/show/NCT04505722

Interesting to note estimated completion dates for the studies. Considering that some of the trials were paused, they came pretty close to their estimates. Pfizer's study is much broader, so their dates are much farther out (you have to read the definitions of what the various dates mean in terms of milestones reached).

edit: More on the various vaccines - costs, storage requirements, etc.

https://apnews.com/article/ast...f6fde45a1edc002ff028

24 November 2020, 12:03 PM

wtg

quote:
Public health officials and drugmakers must be transparent about the side effects people may experience after getting their first shot of a coronavirus vaccine, doctors urged during a meeting Monday with CDC advisors as states prepare to distribute doses as early as next month.

Dr. Sandra Fryhofer of the American Medical Association noted that both Pfizer’s and Moderna’s Covid-19 vaccines require two doses at varying intervals. As a practicing physician, she said she worries whether her patients will come back for a second dose because of the potentially unpleasant side effects they may experience after the first shot.

“We really need to make patients aware that this is not going to be a walk in the park,” Fryhofer said during a virtual meeting with the Advisory Committee on Immunization Practices, or ACIP, an outside group of medical experts that advise the CDC. She is also a liaison to the committee. “They are going to know they had a vaccine. They are probably not going to feel wonderful. But they’ve got to come back for that second dose.”

Participants in Moderna and Pfizer’s coronavirus vaccine trials told CNBC in September that they were experiencing high fever, body aches, bad headaches, daylong exhaustion and other symptoms after receiving the shots. While the symptoms were uncomfortable, and at times intense, the participants said they often went away after a day, sometimes sooner, and that it was better than getting Covid-19.

Both companies acknowledged that their vaccines could induce side effects that are similar to symptoms associated with mild Covid-19, such as muscle pain, chills and headache.

One North Carolina woman in the Moderna study who is in her 50s said she didn’t experience a fever but suffered a bad migraine that left her drained for a day and unable to focus. She said she woke up the next day feeling better after taking Excedrin but added that Moderna may need to tell people to take a day off after a second dose.

“If this proves to work, people are going to have to toughen up,” she said. “The first dose is no big deal. And then the second dose will definitely put you down for the day for sure. ... You will need to take a day off after the second dose.”

https://www.cnbc.com/2020/11/2...lk-in-the-park-.html

24 November 2020, 01:37 PM

CHAS

quote:
Originally posted by Steve Miller:
My friend says he'll get both of them - one in each arm.

If they come out with a third one he'll figure out some other place to inject it.

I am now ready for a shot in each arm and one in the a**, today.

24 November 2020, 06:04 PM

pianojuggler

I got my shingles shots last year. The first one knocked me on my behind for a week. The second one was almost as bad... I took the full week off since by the time the symptoms were gone, I was wiped out from being wiped out.

So... two full weeks of sick leave for one vaccination.

The covid one sounds less disruptive.

24 November 2020, 06:57 PM

QuirtEvans

Got my flu shot today!

24 November 2020, 08:50 PM

Nina

My shingles shot sat me down for maybe 2 days--not really sick, just blah, and a sore arm for maybe 5 days. Still better than getting shingles!

My 2nd dose is due in right after the new year.

24 November 2020, 09:07 PM

AdagioM

quote:
Originally posted by CHAS:
quote:
Originally posted by Steve Miller:
My friend says he'll get both of them - one in each arm.

If they come out with a third one he'll figure out some other place to inject it.

I am now ready for a shot in each arm and one in the a**, today.

Two cheeks, where’s the 4th vaccine?!

24 November 2020, 10:57 PM

Piano*Dad

quote:
Originally posted by QuirtEvans:
Got my flu shot today!

Laggard ...

01 December 2020, 06:40 PM

wtg

CDC announces its recommendations for who gets the vaccine first.

https://www.cnn.com/2020/12/01...tion-vote/index.html

Gov. Pritzker said today that Illinois will get 110,000 doses of the Pfizer in the first delivery, which means 55,000 people.

Long way to go.

01 December 2020, 06:43 PM

Piano*Dad

I'm hopeful my wife will be in the first group. So is she ...

That will at least take one vector (hopefully) out of circulation. I'm not essential, but my age might put me closer to the top of the queue than many folks.

02 December 2020, 12:41 AM

Cindysphinx

quote:
Originally posted by Mikhailoh:
I cannot for the life of me imagine why anyone would not get it.

If it were offered to me tomorrow, I would pass.

It is an untested vaccine that was rushed to market and we do not know the short or long term safety.

Now, that’s easy for me to say. I live in an area where people mask up. I can work from hone indefinitely. I have no risk factors other than age. And if I got the vaccine, where am I going? It’s not like the world will be normal any time soon, so what would I be missing?

If others want the vaccine, you do you. Me, I’m going to see what happens to the people who stick their arms out first.