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Nerve regeneration

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27 March 2024, 11:59 AM
wtg
Nerve regeneration
quote:
Damage to the optic nerve can lead to irreversible blindness. A newly investigated regeneration factor could change that, UConn researchers report in the May 2024 issue of Experimental Neurology.

Blindness and vision impairment due to optic nerve damage affect more than 3 million people in the US alone, according to the Centers for Disease Control (CDC). The most common reason for that damage is glaucoma, a family of eye diseases that affect the flow of liquid in the eye, eventually damaging the long bundle of cells that connect the retina to the brain. That bundle of cells is the optic nerve. They don’t grow back after being damaged, leading to permanent vision loss.

Now, a team of researchers in the lab of UConn School of Medicine neuroscientist Ephraim Trakhtenberg have shown that a protein previously thought unimportant can stimulate regrowth of nerve cells. The protein is called nuclear factor erythroid 3 (Nfe3), and it is unique to nerves originating in the retina. Normally it is not produced by adult neurons.


https://today.uconn.edu/2024/0...placement=newsletter


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We are all visitors to this time, this place. We are just passing through. Our purpose here is to observe, to learn, to grow, to love… and then we return home. - Australian Aboriginal proverb

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27 March 2024, 12:16 PM
Piano*Dad
As someone whose left optic nerve is more than half gone, this is intriguing. Especially since it doesn't seem to have inflammatory side effects that could worsen glaucoma.

Needs to be coupled with something to slow or reverse age-related macular degeneration.
27 March 2024, 12:17 PM
wtg
I sent the article to my friend the eye researcher. I'll share her comments if she responds...


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We are all visitors to this time, this place. We are just passing through. Our purpose here is to observe, to learn, to grow, to love… and then we return home. - Australian Aboriginal proverb

Bazootiehead-in-training